Bayern Munich and Barcelona registered easy wins, while Manchester United came from behind to beat CSKA Moscow 2-1 and Chelsea surrendered the top spot after a 1-1 at home against Atletico Madrid.
Images from Champions League matches played across Europe on Tuesday
Photos from the Champions League matches played across Europe on Tuesday
IMAGES from the UEFA Champions League last 16 first leg matches played across Europe on Tuesday
Portugal's Cristiano Ronaldo celebrated his Madeira homecoming with an early strike but Sweden wrecked the party by hitting back from two down to win 3-2.
Images from the Champions League matches played across Europe on Wednesday.
Holders Spain suffered their first defeat in qualifying for a major tournament in eight years when Miroslav Stoch nodded a late goal to earn Slovakia a shock 2-1 victory in Euro 2016 Group C on Thursday.
Anthony Martial went from villain to hero as his second-half equaliser earned Manchester United a deserved point in a 1-1 draw against CSKA Moscow in Champions League Group B on Wednesday.
World champions Germany drew 1-1 with Spain in a high tempo friendly on Friday as they launched their preparations for a title defence in Russia while their opponents had striker Diego Costa making his long-awaited comeback as a substitute.
A summary of Wednesday night's matches inthe UEFA Champions League.
Photos from the Champions League matches played on Wednesday.
Photos from the Champions League matches played across Europe on Tuesday
Photos from the Euro 2016 qualifying matches played on Sunday.
Photos from the Champions League matches played across Europe on Tuesday
